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May possibly make these circumstances even worse. Dehydration or Hypovolemia—Has to be corrected initially ahead of applying this medicine. Hemophilia (bleeding problem) or Reye's syndrome or Severe asthma, asthma with nasal polyps and runny nose, problems breathing, or other lung difficulties or Stomach or bowel blockage (which includes paralytic ileus) or Surgical procedure (eg, nasopharyngeal tonsils, tonsils)—Should not be used in patients with these situations. Kidney disease or Liver disease—Use with caution. The effects can be enhanced as a consequence of slower elimination of the medicine from the human body. Good Use

Therefore, using dihydrocodeine really should be prevented though the patient is taking MAOIs and for 2 weeks soon after MAOI discontinuation.

Cyclizine có thể làm mất lợi ích về huyết động học của opioid khi sử dụng đồng thời.

When prescribing opioids with serotonergic medicines, consider the potential risk of a drug-drug interaction leading to serotonin syndrome.

The chance of creating serotonin syndrome differs involving different opioid and serotonergic medicine combos

NSAIDs are also used in medicines you can buy from pharmacies, including cough and cold remedies. Prior to taking any other medicines, Verify the label to discover should they contain aspirin, ibuprofen or other NSAIDs.

Infusions usually are not a substitute for Recurrent evaluate in the patient's medical point out. Intramuscular naloxone is really an alternative in case IV access is impossible. Given that the duration of action of naloxone is comparatively shorter, the patient must be carefully monitored till spontaneous respiration is reliably re-set up. Naloxone is usually a aggressive antagonist and huge doses (4 mg) could possibly be expected in severely poisoned patients. For significantly less significant overdosage, administer naloxone 0.2 mg intravenously followed by increments of 0.one mg just about every 2 minutes if required.

Some individuals with circumstances that have to have long-term pain relief might have to take dihydrocodeine for any long time.

▪ Usually do more info not drive till you understand how the medicine affects you. ▪ It really is an offence to drive while you have this medicine in Your system over a specified Restrict Unless of course you have a defence (called the 'statutory defence'). ▪ This defence applies when:

Sedative medicines which include benzodiazepines or connected drugs: The concomitant usage of opioids with sedative medicines like benzodiazepines or related drugs boosts the hazard of sedation, respiratory depression, coma and Loss of life as a result of additive CNS depressant outcome. The dose and period of concomitant use needs to be confined (see section four.four).

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Often speak to your Health care company to ensure the information displayed on this page applies to your personal circumstances.

The initial dihydrocodeine product, Paracodin, is surely an elixir of dihydrocodeine hydroiodide also available as a Tussionex-design and style suspension in lots of European countries.

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